Researchers in Sweden used the largest registry of twin siblings in the world to identify the differences in the etiology of knee osteoarthritis (OA). Their study, “Nature vs nurture in knee osteoarthritis – the importance of age, sex and body mass index,” appears in the April 2019 edition of Osteoarthritis and Cartilage.

Co-author Karin Magnusson, Ph.D., P.T., post doc in the Clinical Epidemiology Unit, Orthopedics, Department of Clinical Sciences at Lund University in Sweden, explained the rationale behind her study, “Familial factors such as genetics and body weight are well-known risk factors for knee OA for men and women. However, the association between the genetic contribution to knee OA and body weight for men and women across the life span had not been previously studied…”1

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